Category Archives: Antioxidants

Fighting Off Winter Illness With the Help of Vitamin C

Fight-Winter-Illness-Vitamin-C

With winter approaching, the majority of us modify our skincare routines, what we wear, and even what we eat in response to the colder, drier air. In addition to weather changes, winter also brings cold and flu season. Fortunately, changing your supplement routine to include Vitamin C supplements may help prepare your immune system for winter and shorten any colds or cases of flu you do catch. Read on to learn interesting facts about Vitamin C and its relationship to illnesses.

Vitamin C and Its Relationship to Winter Illnesses

  • Vitamin C, also known as L-Ascorbic Acid, is the most well-known antioxidant and Vitamin C supplements are the most commonly used supplement.
  • During the winter months, Vitamin C rich fruits are typically out of season. This can make supplements especially helpful for reaching the required daily dose.
  • Since it functions as an antioxidant, C is a well-known immune booster. It helps battle flu symptoms, shorten the duration of colds, and produce collagen.
  • When you are stressed, your body needs additional L-Ascorbic Acid. Consider grabbing an orange or a supplement to keep your immune system from being dragged down by the effects of stress. According to the book, “Boost Your Immune System Naturally” by Gary Singh, free radicals can get out of control during infections. Additional amounts of C can help “mop up” extra free radicals and help the body fight infection. The book also states that this powerful antioxidant may play a role in assisting white blood cells in destroying harmful invaders such as bacteria and viruses.
  • The minimum dose of this antioxidant is 60mg per day. It is crucial to ensure you are getting this amount through food or supplements.
  • In addition to Vitamin C, Iron and Vitamin B can also be helpful for staying healthy during the winter months.

Final Thoughts

Since you are probably crossing your fingers that you stay healthy this winter, make sure that you reach the dietary requirements for Vitamin C each day either through food or supplements. Although it cannot prevent sickness completely, it may boost your body’s ability to heal quicker.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Vitamin C and Workout Recovery

Workout-Recovery-Vitamin-C

Whether you’re brand new to working out, or a veteran fitness buff, muscle recovery is a key factor in avoiding injury. Did you know that Vitamin C has been proven to aid in workout recovery? Here are a few ways this powerhouse vitamin can keep you from getting sidelined.

1) It Packs an Antioxidant Punch

Antioxidants are nutrients that block damage created by free radicals. Not only can free radicals speed the aging process of our skin, but they can also speed the rate at which our muscles break down. Adding Vitamin C to your health regimen will boost your defense against free radicals and protect your muscles after a hard workout.

2) It Fights Inflammation

Vitamin C helps boost our metabolism. Great for losing weight, but also helpful in blocking proteins that are actually harmful to our bodies. The synthesis of certain proteins can increase the risk of inflammation and infection. The more inflammation, the greater the risk of muscle injury. By blocking the chemical reactions in your body that can lead to inflammation, you’ll experience less muscle soreness and be less likely to experience an injury.

3) It Boosts Immunity

After putting your body through a grueling workout, all of your internal systems are working hard on recovery. During this time, you may experience a temporary dip in your body’s ability to fight infection. Vitamin C protects your body against the onslaught of germs, digestive distress, and other potentially harmful after-effects.

4) It Knocks Out Cortisol

Cortisol is a stress hormone that increases during times that our bodies are under stress or extreme exertion. We store excess cortisol, and it can lead to an increase in fat around our midsections. Vitamin C helps lower cortisol levels after a workout, preventing the storage of excess levels and that pesky abdominal fat.

Increasing your Vitamin C intake is a simple way to help your body recover quickly from your workouts and prepare you for your next one. Don’t risk injury or illness by neglecting to add this important vitamin to your daily regimen.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Your Heart Health and Vitamin C

vitamin c suppliements heart health

Vitamin C, also referred to as ascorbic acid, is one of the most well-known antioxidants. Linus Pauling, a two-time Nobel Prize winner, pioneered the majority of research surrounding this powerful vitamin and its numerous health benefits.

More research has been conducted on this antioxidant than almost any other nutrient. For starters, it has been shown to help prolong the onset of cataracts by a decade. It also plays a crucial role in joint, bone, and immune health. Arguably, one of its most important roles is supporting heart health.

Vitamin C and Heart Health

Ascorbic acid has been proven to provide the heart with a variety of benefits:

  • It enhances the level of natural glutathione in the body and thereby helps prevent coronary artery disease.
  • As a potent scavenger of free radicals, it helps protect arteries.
  • It helps strengthen blood vessels walls by supporting the synthesis of collagen. If collagen is weak, oxidized LDL, heavy metals, and toxins create inflammation in the vascular lining. This is how atherosclerotic plaque begins to form.
  • Vitamin C helps improve vasodilation, the ability of arteries in the heart to widen to accommodate more blood when needed – this is one of the main factors in decreasing the risk of heart disease. It improves vasodilation by increasing Nitric Oxide’s availability. Nitric Oxide is a promoter of vasodilation.

What Does the Research Say?

recent meta-analysis analyzed the effect of antioxidant supplements on arterial stiffness. The results indicated that antioxidant supplements played a significant role in helping to reduce arterial stiffness. However, decreased arterial stiffness was only observed in studies that used ascorbic acid combined with other antioxidants, such as Vitamin E. Additionally, antioxidant supplementation was the most effective in patients that already had low concentrations of Vitamins E and C in their plasma.

How to Obtain It

Vitamin C is classified as an “essential nutrient”. This means it is not manufactured by our body and must be consumed in foods or supplements. Foods rich in this antioxidant include tomatoes, citrus fruits, broccoli, strawberries, watermelon, and kiwis. Vitamin C supplements are another very effective method in meeting your daily requirements for this key vitamin.

 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Which Organs Benefit from a Boost in Vitamin C?

vitamin c boost

While many of us know that Vitamin C helps support a healthy immune system, it also plays important roles in the health and maintenance of other organ systems. From our heart to our skin, let’s take a look at which of our bodies’ systems benefit from a boost in Vitamin C.

Cardiovascular Health

Vitamin C can be a big part of maintaining healthy blood pressure levels. Keeping blood pressure within a healthy range is important to prevent heart disease and reduce the risk of a stroke. In fact, a study from the American Journal of Clinical Nutrition found that people with higher levels of baseline plasma vitamin C had a 42% lower risk for stroke.

Skin Health

Vitamin C is also a factor when it comes to keeping your skin healthy. A double-blind, placebo-controlled study revealed that taking liposomal Vitamin C every day can help your skin age gracefully by increasing skin firmness and reducing the appearance of fine lines and wrinkles.1 This may happen because the body uses vitamin C to produce collagen. Collagen is the most abundant protein in the body. It provides structure to many parts of the body, including bones, skin, tendons and ligaments, and is a key part of connective tissue that helps maintain firm and healthy skin.

Muscular Health

As discussed earlier, Vitamin C is essential to the natural production of collagen, which plays many roles in the muscular system.  Collagen makes up the connective tissue found in tendons and blood vessels, and muscles throughout the body.  Vitamin C may also help reduce the build-up of lactic acid during exercise and promote muscle recovery from normal exercise.

1 LivOn Labs, Princeton Consumer Research (2014) A Double-blind, Home-Use Study in Approximately 45 Healthy Volunteers with Aging, Non-Firm Skin to Assess the Efficacy or Different Treatment Dosages of a Vitamin C Dietary Supplement Compared to a Placebo Control Group.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

4 Reasons Vitamin C is Great for Skin Care 

vitamin c supplement

It’s no secret that our bodies need Vitamin C. It supports healthy immunity, prevents scurvy, and helps us feel good from day to day. But did you know that Vitamin C is also great for your skin? Here are four of the many reasons you should add Vitamin C to your skin care routine.

What is Glutathione (GSH)?

GSHBanner

If you’re reading this, odds are you have seen the term “Glutathione” (GSH) before. But how much do you know about this powerful antioxidant? Do you know that it has been touted as the “next big antioxidant” or “the master defender” by health professionals world wide? If not, listen up.

Glutathione offers countless benefits related to joints, eyes, the brain and lungs. Yet, market research suggests that fewer than 6% of consumers are familiar with it. How could this be?

GSH is the most prevalent antioxidant produced by the human body. Healthy cells actually produce Glutathione. When cells run out of GSH, they die! GSH production naturally declines with age. So, supplementation of this vital antioxidant is paramount.

Glutathione

  • Helps protect cells from the damage caused by harmful free radicals
  • Promotes detoxification and optimal cellular health
  • Supports a healthy liver and immune system

Glutathione deficiencies have been linked to many chronic, difficult to treat illnesses. (Here is your chance to start that online search we mentioned earlier!). In addition to its powerful effects inside the body, Glutathione has been used for decades all over the world to improve skin clarity, tone and texture.

A study published in the European Journal of Nutrition revealed that daily supplementation of Setria® Glutathione – the form of L-Glutathione used in Lypo-Spheric™ Glutathione – is effective at increasing body stores of Glutathione by 30-35% over a 6 month period.

It’s probably time for you to give Gluathione a try. With our 100% money back guarantee, what have you got to lose?

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Important Role of Vitamin C

Important Roles of Vitamin C

Many people assume Vitamin C is only required in tiny amounts; just enough to prevent scurvy. After all, this Vitamin C-deficiency disease spawned the chemical name ascorbate for Vitamin C. Ascorbate literally means “against scurvy.” Were this its only function, tiny amounts of Vitamin C would be sufficient for most people on the planet. But, there’s vastly more it can do.

Vitamin C is required in many essential metabolic processes – two of which we have highlighted below: Collagen Synthesis and Calcium Incorporation.

Collagen Synthesis

Vitamin C is essential for the synthesis and maintenance of collagen, the most abundant protein in the human body. Collagen comprises about 25% to 35% of the total protein content in the body. Its strong, connective, elongated fibrils are found in skin, ligaments, tendons, cartilage, bone, blood vessels, the intestines, and the discs between spinal vertebrae. It is also found in the cornea and in muscle tissue.

  • Vitamin C helps protect the skin by promoting the production and migration of fibroblasts that support normal wound healing.
  • VitaminC protects against skin wrinkles seen in premature aging.
  • Increased VitaminC uptake by vascular smooth muscle cells increases the synthesis and maturation of Type I (aka Type 1) collagen.  Type I collagen accounts for about 90% of the body’s total collagen content.
  • High concentrations of VitaminC stimulate synthesis of Type IV collagen, which has important filtration characteristics in the kidney, the blood-brain barrier, and the arterial lining .

Promotes Calcium Incorporation into Bone Tissue

The formation and maintenance of quality, high-density bone material requires Vitamin C. Vitamin C promotes assimilation of calcium into the bone, protects against leaching of calcium out of the bones, and fights the oxidative stress that works against assimilation.

  • Vitamin C stimulates the formation of the cells that incorporate calcium into bone tissue (osteoblasts).
  • VitaminC inhibits the development of cells that dissolve calcium out of bone tissues (osteoclasts).
  • As a powerful antioxidant, VitaminC fights oxidative stress in bone tissues.
  • Collagen cross-linking, required to form the dense matrix for optimal bone strength, requires Vitamin C.

Vitamin C is essential to numerous functions inside the body. We’ve just outlined two more reasons to get your daily dose!

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

17 Ways Vitamin C Supports a Healthy Immune System

The power of vitamin C is often attributed to its role as an antioxidant. However, no other antioxidant can perform the many additional physiological and biological roles that vitamin C fills. To think of vitamin C as nothing more than an antioxidant would be a great understatement.

Among its many positive effects on the body, vitamin C is a strong supporter of healthy immune function. Here’s how:

  1. Vitamin C supports the production of interferons. Interferons are produced when the presence of pathogens is detected. They facilitate the ability of cells to launch protective cellular defenses.*

  2. Vitamin C enhances the function of phagocytes. Phagocytes are a type of white blood cell that envelop pathogens and other dangerous particles. Once the invaders are captured in this manner, they are enzymatically digested.*

  3. Vitamin C supports the cell-mediated immune response. There are 2 major ways that the body can respond to a pathogen: antibody-mediated immunity and cell-mediated immunity. Cell-mediated response refers to the activation of macrophages, natural killer cells, and antigen-specific T-lymphocytes that attack anything perceived as a foreign agent.*

  4. Vitamin C neutralizes oxidative stress.*

  5. Vitamin C improves and enhances the immune response achieved with vaccination.*

  6. Vitamin C enhances cytokine production by white blood cells. Cytokines are communication proteins released by certain white blood cells that transmit information to other cells, promoting the immune response.*

  7. Vitamin C inhibits various forms of T-lymphocyte death. T-lymphocytes are a type of white blood cell. They are an integral part of the cell-mediated immune defense system. Vitamin C helps to keep these important cells alive and viable.*

  8. Vitamin C enhances nitric oxide production by phagocytes. Phagocytes, as discussed in #2, are white blood cells that engulf invading microorganisms. Nitric oxide is produced in large amounts in these cells, and it is one of the agents that will kill captured pathogens.*

  9. Vitamin C enhances T-lymphocyte production. As mentioned in #7, these cells are essential to cell-mediated immune responses, and Vitamin C helps them to multiply in number.*

  10. Vitamin C enhances B-lymphocyte production. These white blood cells make antibodies as part of the antibody-mediated immune response. Antibodies are formed in reaction to the initial introduction of an invading pathogen or antigen.*

  11. Vitamin C inhibits neuraminidase production. Some pathogenic viruses and bacteria create neuraminidase, an enzyme that keeps them from being trapped in mucus, one of the body’s natural lines of defense. Inhibiting neuraminidase helps the body optimize this defensive mechanism.*

  12. Vitamin C supports antibody production and activity. Good antibody function is important to a healthy immune system.*

  13. Vitamin C supports natural killer cell activity. Natural killer cells are lymphocytes that can directly attack cells, like tumor cells, and kill them.*

  14. Vitamin C supports localized generation and interaction with hydrogen peroxide. Vitamin C and hydrogen peroxide can kill microorganisms and can dissolve the protective capsules of some bacteria, such as pneumococci. *

  15. Vitamin C enhances cyclic GMP levels in lymphocytes. Cyclic GMP plays a central role in the regulation of many physiologic responses, including the modulation of immune responses. Cyclic GMP is important for normal cell proliferation and differentiation. It also controls the action of many hormones, and it appears to mediate the relaxation of smooth muscle.*

  16. Vitamin C detoxifies histamine. This effect is important in the support of local immune factors.*

  17. Vitamin C enhances the mucolytic effect. This property helps liquefy thick secretions, increasing immune access to infection.*

  18. Vitamin C makes bacterial membranes more permeable to some antibiotics. *

  19. Vitamin C enhances prostaglandin formation. Prostaglandins are hormone-like compounds that control many physiologic processes, including regulating T-lymphocyte function.*

  20. Vitamin C concentrates in white blood cells. Some of the primary cells in the immune system concentrate Vitamin C as much as 80 times higher than the level in plasma. This assures extra delivery of Vitamin C to the sites of infection by the migration of these Vitamin C-rich white blood cells.*

References
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[2] Siegel B, “Enhancement of interferon production by poly(rI)-poly(rC) in mouse cell cultures by ascorbic acid” Nature 1975 254(5500):531-532.
[3] Geber W, Lefkowitz S, Hung C, “Effect of ascorbic acid, sodium salicylate, and caffeine on the serum interferon level in response to viral infection” Pharmacology 1975 13(3):228-233.
[4] Dahl H ,Degre M, “The effect of ascorbic acid on production of human interferon and the antiviral activity in vitro. Acta Pathologica et Microbiologica Scandinavica. Section B” Microbiology 1976 84(5):280-284.
[5] Stone I, “The possible role of mega-ascorbate in the endogenous synthesis of interferon” Medical Hypotheses 1980 6(3):309-314.
[6] Karpinska T, Kawecki Z, Kandefer-Szerszen M, “The influence of ultraviolet irradiation, L-ascorbic acid and calcium chloride on the induction of interferon in human embryo fibroblasts” Archivum Immunologiae et Therapiae Experimentalis 1982 30(1-2)33-37.
[7] Nungester W, Ames A, “The relationship between ascorbic acid and phagocytic activity” Journal of Infectious Diseases 1948 83:50-54.
[8] Goetzl E, et al, “Enhancement of random migration and chemotactic response of human leukocytes by ascorbic acid” The Journal of Clinical Investigation 1974 53(3):813-818.
[9] Sandler J, Gallin J, Vaughan M, “Effects of serotonin, carbamylcholine, and ascorbic acid on leukocyte cyclic GMP and chemotaxis” The Journal of Cell Biology 1975 67(2 Pt 1):480-484.
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[12] Anderson R, Dittrich O, “Effects of ascorbate on leucocytes. Part IV. Increased neutrophil function and clinical improvement after oral ascorbate in 2 patients with chronic granulomatous disease” South African Medical Journal 1979 56(12):476-480.
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[16] Dallegri F, Lanzi G, Patrone F, “Effects of ascorbic acid on neutrophil locomotion” International Archives of Allergy and Applied Immunology 1980 61(1):40-45.
[17] Corberand J, et al, “Malignant external otitis and polymorphonuclear leukocyte migration impairment. Improvement with ascorbic acid” Archives of Otolaryngology 1982 108(2):122-124.
[18] Patrone F, et al, “Effects of ascorbic acid on neutrophil function. Studies on normal and chronic granulomatous disease neutrophils” Acta Vitaminologica et Enzymologica 1982 4(1-2):163-168.
Cunningham-Rundles S, “Effects of nutritional status on immunological function” The American Journal of Clinical Nutrition 1982 35(5 Suppl):1202-1210.
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[20] Levy R, Schlaeffer F, “Successful treatment of a patient with recurrent furunculosis by vitamin C: improvement of clinical course and of impaired neutrophil functions” International Journal of Dermatology 1993 32(11):832-834.
[21] Levy R, et al, “Vitamin C for the treatment of recurrent furunculosis in patients with impaired neutrophil functions” The Journal of Infectious Diseases 1996 173(6):1502-1505.
[22] Ciocoiu M, et al, “The involvement of vitamins C and E in changing the immune response” [Article in Romanian] Revista Medico-Chirurgicala a Societatii de Medici si Naturalisti din Iasi 1998 102(1-2):93-96.
De la Fuente M, et al, “Immune function in aged women is improved by ingestion of vitamins C and E” Canadian Journal of Physiology and Pharmacology 1998 76(4):373-380.
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[24] Thomas W, Holt P, “Vitamin C and immunity: an assessment of the evidence” Clinical and Experimental Immunology 1978 32(2):370-379.
[25] Evans R, Currie L, Campbell A, “The distribution of ascorbic acid between various cellular components of blood, in normal individuals, and its relation to the plasma concentration” The British Journal of Nutrition 1982 47(3):473-482.
[26] Goldschmidt M, “Reduced bactericidal activity in neutrophils from scorbutic animals and the effect of ascorbic acid on these target bacteria in vivo and in vitro” The American Journal of Clinical Nutrition 1991 54(6 Suppl):1214S-1220S.
[27] Washko P, Wang Y, Levine M, “Ascorbic acid recycling in human neutrophils” The Journal of Biological Chemistry 1993 268(21):15531-15535.
[28] Siegel B, Morton J, “Vitamin C and the immune response” Experientia 1977 33(3):393-395.
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Campbell J, et al, “Ascorbic acid is a potent inhibitor of various forms of T cell apoptosis” Cellular Immunology 1999 194(1):1-5.
[29] Mizutani A, et al, “Ascorbate-dependent enhancement of nitric oxide formation in activated macrophages. Nitric Oxide: Biology and Chemistry 1998 2(4):235-241.
[30] Mizutani A. Tsukagoshi N, “Molecular role of ascorbate in enhancement of NO production in activated macrophage-like cell line, J774.1” Journal of Nutritional Science and Vitaminology 1999 45(4):423-435.
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[32] Wu C, Dorairajan T, Lin T, “Effect of ascorbic acid supplementation on the immune response of chickens vaccinated and challenged with infectious bursal disease virus” Veterinary Immunology and Immunopathology 2000 74(1-2):145-152.
[33] Schwager J, Schulze J, “Influence of ascorbic acid on the response to mitogens and interleukin production of porcine lymphocytes” International Journal for Vitamin and Nutrition Research 1997 67(1):10-16.
[34] Rotman D, “Sialoresponsin and an antiviral action of ascorbic acid” Medical Hypotheses 1978 4(1):40-43.
[35] Ecker E, Pillemer L, “Vitamin C requirement of the guinea pig” Proceedings of the Society for Experimental Biology and Medicine 1940 44:262.
[36] Bourne G, “Vitamin C and immunity” The British Journal of Nutrition 1949 2:342.
Prinz W, et al, “The effect of ascorbic acid supplementation on some parameters of the human immunological defence system” International Journal for Vitamin and Nutrition Research 1977 47(3):248-257.
[37] Vallance S, “Relationships between ascorbic acid and serum proteins of the immune system” British Medical Journal 1977 2(6084):437-438.
[38] Sakamoto M, et al, “The effect of vitamin C deficiency on complement systems and complement components” Journal of Nutritional Science and Vitaminology 1981 27(4):367-378.
Feigen G, et al, “Enhancement of antibody production and protection against systemic anaphylaxis by large doses of vitamin C” Research Communications in Chemical Pathology and Pharmacology 1982 38(2):313-333.
[39] Li Y, Lovell T, “Elevated levels of dietary ascorbic acid increase immune responses in channel catfish” The Journal of Nutrition 1985 115(1):123-131.
[40] Wahli T, Meier W, Pfister K, “Ascorbic acid induced immune-mediated decrease in mortality in Ichthyophthirius multifiliis infected rainbow-trout (Salmo gairdneri)” Acta Tropica 1986 43(3):287-289.
[41] Johnston C, Kolb W, Haskell B, “The effect of vitamin C nutriture on complement component C1q concentrations in guinea pig plasma” The Journal of Nutrition 1987 117(4):764-768.
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[43] Wu C, Dorairajan T, Lin T, “Effect of ascorbic acid supplementation on the immune response of chickens vaccinated and challenged with infectious bursal disease virus” Veterinary Immunology and Immunopathology 2000 74(1-2):145-152.
[44] Heuser G, Vojdani A, “Enhancement of natural killer cell activity and T and B cell function by buffered vitamin C in patients exposed to toxic chemicals: the role of protein kinase-C” Immunopharmacology and Immunotoxicology 1997 19(3):291-312.
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[48] Atkinson J, et al, “Effects of ascorbic acid and sodium ascorbate on cyclic nucleotide metabolism in human lymphocytes” Journal of Cyclic Nucleotide Research 1979 5(2):107-123.
[49] Panush R, et al, “Modulation of certain immunologic responses by vitamin C. III. Potentiation of in Vitro and in vivo lymphocyte responses” International Journal for Vitamin and Nutrition Research. Supplement 1982 23:35-47.
[50] Strangeways W, “Observations on the trypanocidal action in vitro of solutions of glutathione and ascorbic acid” Annals of Tropical Medicine and Parasitology 1937 31:405-416.
[51] Miller T, “Killing and lysis of gram-negative bacteria through the synergistic effect of hydrogen peroxide, ascorbic acid, and lysozyme” Journal of Bacteriology 1969 98(3):949-955.
[52] Tappel A, “Lipid peroxidation damage to cell components” Federation Proceedings 1973 32(8):1870-1874.
[53] Kraut E, Metz E, Sagone A, “In vitro effects of ascorbate on white cell metabolism and the chemiluminescence response” Journal of the Reticuloendothelial Society 1980 27(4):359-366.
[54] Robertson W, Ropes M, Bauer W, “The degradation of mucins and polysaccharides by ascorbic acid and hydrogen peroxide” The Biochemical Journal 1941 35:903.
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[56] Johnston C, Martin L, Cai X, “Antihistamine effect of supplemental ascorbic acid and neutrophil chemotaxis” Journal of the American College of Nutrition 1992 11(2):172-176.
[57] Kastenbauer S, et al, “Oxidative stress in bacterial meningitis in humans” Neurology 2002 58(2):186-191.
[58] Versteeg J, “Investigations on the effect of ascorbic acid on antibody production in rabbits after injection of bacterial and viral antigens by different routes. Proceedings of the Koninklijke Nederlandse Akademie van Wetenschappen. Series C” Biological and Medical Sciences 1970 73(5):494-501.
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[60] Wu C, Dorairajan T, Lin T, “Effect of ascorbic acid supplementation on the immune response of chickens vaccinated and challenged with infectious bursal disease virus” Veterinary Immunology and Immunopathology 2000 74(1-2):145-152.
[61] Ericsson Y, “The effect of ascorbic acid oxidation on mucoids and bacteria in body secretions” Acta Pathologica et Microbiologica Scandinavica 1954 35:573-583.
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©2014 LivOn Labs. Content adapted from Primal Panacea by Thomas E. Levy, MD, JD.

More Insulin = More Fat

insulin and fat

You know those who claim to have been blessed with a “fast” metabolism? Yes, they bug us, too….. It seems some have innate systems that allow them to process sugars, starches, fats and calories more efficiently. With the holiday season upon us, an efficient calorie and fat burning system is on many of our wish lists.

What you may not know is that your entire metabolic system may not be to blame for that layer of fat you can’t seem to banish – the culprit may be insulin sensitivity.

<div class=”callout”>Insulin is a hormone that regulates the metabolism of carbohydrates and fats.</div>

Whenever you eat carbohydrates or protein, the level of sugar in your blood increases. In healthy individuals, insulin is released from the pancreas to remove the excess sugar from the blood, which otherwise would be toxic. This sugar is then used for energy. If your body is not responding properly to the insulin (poor insulin sensitivity), it begins to over-produce insulin in order to keep blood sugar levels in check. This can be the thing standing between you and your fat loss goals, because insulin has a powerful ability to prevent the breakdown of fat.

More Insulin Equals More Fat

What can you do to improve your insulin sensitivity? Fitness professionals have relied on one particular supplement for years. Some would say it’s one of the best kept secrets to weight management…. R-Alpha Lipoic Acid (or R-ALA).

Multiple placebo controlled studies have shown that daily doses of 600 mg to 1800 mg of ALA can improve insulin sensitivity and the utilization of glucose, ultimately leading to healthy blood sugar levels.

ALA may also go a step further and help prevent the complications that are associated with unhealthy blood sugar levels, specifically complications in the vascular system and kidneys. Recent research indicates this reduced threat of complication comes from ALA’s ability to protect the inner lining of blood vessels (the endothelium) from damage caused by oxidative stress.

It’s important to note that all R-ALA supplements are not created equal. Research shows that R -Alpha Lipoic Acid is a more biologically active form of ALA that offers greater antioxidant and neuroprotective benefits at substantially lower doses than the “S” form of alpha lipoic acid that is more commonly available. The body has a strong preference for natural R-ALA. Be sure to look for this when comparing supplements. Lypo-Spheric™ R-ALA uses the more bioavailable, “R” form of alpha lipoic acid, the form found in nature.

In addition to increasing insulin sensitivity, R-Alpha Lipoic Acid (R-ALA) is one of the body’s most powerful intracellular and extracellular antioxidants. Known as the Universal Antioxidant, R-ALA directly affects the health of nearly every cell in the body, and can even cross the blood-brain barrier. The “R” form of ALA is considered the most bioavailable and biologically active form of ALA in the body. LypriCel™ R-ALA delivers high-quality R-ALA in every packet, neutralizing free radicals in nearly every part of the body.

Give the gift of healthy to nearly every part of the body this holiday season with Lypo-Spheric R-ALA. The heart, brain, eyes and waistline will all thank you for improved insulin sensitivity and reduced damage from free radicals.

Four Key Benefits of Alpha Lipoic Acid

When you hear the name “Alpha Lipoic Acid,” does it sound familiar, but you don’t quite know what it is?  Well, you’re not alone.  Alpha Lipoic Acid (ALA) often plays the role of the supporting actress – it’s a highly versatile antioxidant that’s found in nearly everything, yet is largely underappreciated. Although ALA has enjoyed periods of fame, most notably a mention on Dr. Oz earlier this year, it is often upstaged by more popular antioxidants like Vitamin C.

We happen to believe ALA may just be the most important substance you have never heard of, and it’s time to give it the attention it deserves!

To start, you should know that Alpha Lipoic Acid goes by several names and abbreviations, including ALA, Lipoic Acid, LA, Thioctic Acid, Lipoate, and α-lipoic acid.  Although less commonly used, Alpha Lipoic Acid may also be referred to as 6,8-thioctic acid, 6,8-dithioctane acid, 1,2-dithiol-3-valeric acid, and DHLA.

Now, here are four great reasons to know and love Alpha Lipoic Acid:

ALA = Energy

We all need energy, especially cellular energy. Cellular energy is the power behind every single action within the human body, including muscle movement, generation of new cells, wound healing, and even thinking.  You are using valuable cellular energy right now, just by reading this article!

The body’s supply of cellular energy starts in the mitochondria of the cells.  There are thousands of mitochondria in most eukaryotic cells (cells with nuclei) within the body, and they are constantly creating energy through a process known as the Krebs Cycle.  ALA is an important cofactor to two key enzymatic reactions within this Cycle. To put it simply, without ALA, cellular energy is not possible.  And without cellular energy, life is not possible.

ALA and Healthy Blood Sugar Levels

Another important characteristic of ALA is its effect on insulin, and the body’s use of blood sugar (glucose). Multiple placebo controlled studies have shown that daily doses of 600 mg to 1800 mg of ALA can improve insulin sensitivity and the utilization of glucose, ultimately leading to healthy blood sugar levels.

ALA may also go a step further and help prevent the complications that are associated with unhealthy blood sugar levels, specifically complications in the vascular system and kidneys. Recent research indicates this reduced threat of complication comes from ALA’s ability to protect the inner lining of blood vessels (the endothelium) from damage caused by oxidative stress.

ALA is a Key Factor in Optimal Nerve Health

In Germany, ALA has been approved as a treatment for diabetic neuropathy – a debilitating condition that causes painful burning sensations in the arms and legs, and eventually leads to a loss of nerve function.   Although most of the studies related to this treatment have used intravenous (IV) ALA, a placebo controlled study using oral ALA demonstrated that symptoms of diabetic neuropathy, including pain, stinging and burning sensations, were reduced when taking single doses of 600 mg, 1200 mg or 1800 mg per day for 5 weeks.

ALA is an Important Part of Your Weight-Loss Plan

Every year, thousands of different supplements, gym memberships, pharmaceutical drugs, books, and medical treatments are used by people trying to lose weight.  In 2012, the annual revenue of the USA weight-loss industry was an estimated $20 billion. Clearly, managing a healthy weight is an issue many people struggle with.

Alpha Lipoic Acid cannot magically make cheeseburgers as nutritious as carrots, but it does have an effect on how our bodies use food and excess fat.  Recent research showed that overweight individuals who took 1,800 mg ALA every day for 20 weeks lost more weight than subjects who did not take ALA. It all comes down to cellular energy.  By supporting the creation of energy within the cells, ALA can help stimulate the body to use food molecules more quickly and burn excess calories from fat.

Choosing the Right Form of Alpha Lipoic Acid

ALA can be found in oral supplements in two forms: the R form, which is the form found in nature, or the S form. The R form of ALA is more bioavailable and biologically active than S-ALA, but it is expensive to produce and often presents stability issues in manufacturing. This is why many ALA supplements contain only the S form, or a 50/50 mixture of S-ALA and R-ALA (also referred to as racemic ALA).

In most cases, only 50% of the total dose of supplements labeled as Alpha Lipoic Acid or R/S Lipoic Acid is the R form.  Because R-ALA has only recently become available in a stabilized format, most clinical research has been conducted using intravenous or oral mixtures of R/S ALA.  This is important to consider when choosing how much ALA to take.  For example, when clinical evidence suggests 600 mg of racemic ALA per day can help maintain healthy blood sugar levels, this dose would be equivalent to 300 mg of R-ALA.

Liposome encapsulated R-ALA may also offer further benefits to the absorption and utilization of R-ALA in the body.  ALA pills, powders and capsules are rapidly, but incompletely absorbed into the blood, and then quickly used by the body or passed as waste.  With Liposomal Encapsulation Technology, R-ALA is encapsulated and protected from destruction in the digestive system by microscopic liposomes.  Since liposomes are made of phospholipids (the same material that makes up your cellular membrane), they are capable of passing through cell membranes and delivering R-ALA directly into the cell.

 

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